Effect of Essential Fatty Acid Deficiency on Cutaneous Sterol Synthesis

Effect of essential fatty acid deficiency on cutaneous sterol synthesis.

The fact that the skin is a major site of total body sterologenesis, coupled both with the apparent absence of low density lipoprotein receptors on keratinocytes and with the lack of influence of serum cholesterol on epidermal sterologenesis, has created the impression that epidermal lipid synthesis might be autonomous, i.e., nonregulatable. Recent studies have shown, however, that disruption o...

Diagnosing essential fatty acid deficiency.

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Fat Absorption in Essential Fatty Acid Deficiency*

The various gross symptoms of essential fatty acid deficiency in the rat are well recognized, but little is known about the metabolic features of this disease. The purpose of this investigation was to study the influence of fat deficiency on the rate of absorption and transport of fat through the intestinal mucosa. The scheme of fat labeling by the use of spectroscopically active methyl esters ...

The effect of ;essential fatty acid' deficiency on the fatty acid composition of the total lipid of the intestine.

Srebp2: A master regulator of sterol and fatty acid synthesis.